PARANEOPLASTIC SYNDROMES IN THE PRACTICE OF A NEUROLOGIST (CLINICAL CASES)
DOI:
https://doi.org/10.21802/2304-7437-2019-5(57)-44-51Keywords:
paraneoplastic syndromes, clinical cases, cancer non-cancerous antibodies, polyneuropathy.Abstract
Paraneoplastic syndromes are the rare states caused by a change in the immune system's response to neoplasms. These include non-metastatic systemic effects that accompaniy malignant diseases. Diagnosis of these syndromes has some difficulties. In this article clinical cases of patients with paraneoplastic syndromes are analyzed and differential diagnosis is performed. Careful analysis of each clinical case is extremely important for the accumulation of experience, improvement of diagnostics and avoiding mistakes in the future.
References
Абелев Г.И. Что такое опухоль // Соросовский образовательный журнал. – 1997. – № 10. – С. 85–90.
Булбук Г.А. Паранеопластический синдром и опухолевая резистентность организма. – Кишинев: Штиинца, 1987. – 176 с.
Дворецкий Л.И. Паранеопластические синдромы // Трудный диагноз. –2003. – № 3. – С. 165–177.
Онкология : словарь-справочник. – К: Наукова думка, 1992. – 264 с.
Шнейдер Н.А., Дыхно Ю.А., Ежина В.В. Клиническая гетерогенность паранеопластического неврологического синдрома // Сибирский онкологический журн. – 2011. – № 3. – С. 82–90.
Carcinoma associated paraneoplastic peripheral neuropathies in patients with and without anti-onconeural antibodies / Antoine J. C., Mosnier J. F., Absi L., et al. // J. Neurol. Neurosurg. Psychiatry. 1999. Vol. 67, № 1. Р. 7–14.
Gultekin S.H. Recent developments in paraneoplastic disorders of the nervous system // Surg. Pathol. Clin. 2015. Vol. 8, № 1. Р. 89–99.
Pittock S.J., Kryzer T.J., Lennon V.A. Paraneoplastic antibodies coexist and predict cancer, not neurological syndrome // Ann. Neurol. 2004. Vol. 56, № 5. Р. 715–719.
Recommended diagnostic criteria for paraneoplastic neurological syndromes / Graus F., Delattre J. Y., Antoine J. C., et al. // J. Neurol. Neurosurg. Psychiatry. 2004. Vol. 75, № 8. Р. 1135–1140.
Subacute sensoryneuropathy: a remote effect of carcinoma / Horwich M.S., Cho L., Porro R.S., Posner J.B. // Ann. Neurol. 1977. Vol. 2, № 1. Р. 7–19.
Sudheeran Kannoth. Paraneoplastic neurologic syndrome: A practical approach //Ann. Indian Acad. Neurol. 2012. Vol. 15, № 1. Р. 6–12.
Treatment of paraneoplastic neurological syndromes with antineuronal anti-bodies (anti - Hu, anti - Yo) with a combination of immunoglobulins, cyclo-phosphamide, and methylprednisolone / Keime-Guibert F., Graus F., Fleury A., et al. // J. Neurol. Neurosurg. Psychiatry. 2000. Vol. 68, № 4. Р. 479–482.
Frequencyofspecific cancer types in dermatomyositis and polymyositis: a populationbased study / Hill C.l., ZhangY., Sigurgeirsson B., et al. // Lacent. 2001. Vol. 357, № 9250. P. 96–100.