THE EFFECT OF IVABRADINE AND OMEGA-3 POLYUNSATURATED FATTY ACIDS FOR QUALITY OF LIFE OF PATIENTS WITH HEART FAILURE
Keywords:
heart failure, treatment, quality of life, ivabradine, omega-3 polyunsaturated fatty acidsAbstract
The effects of ivabradine and omega-3 polyunsaturated fatty acids (ω-3 PUFA) for quality of life (QoL) of patients with heart failure (HF) were studied. 357 patients with ischemic HF and sinus rhythm were randomized into four groups (due management). QoL was evaluated by MHFLQ and EuroQol-5D questionnaires. Established, that all medication’s schemes caused to improving of QoL of observed patients with HF, but not had influence for psychological status. More strong dynamics of QoL increase was observed in group with additional usage of Ivabradine and ω-3 PUFA. Additional prescription of Ivabradine was more effective for pain/fatigue reduction (OR=2,53; 95% СІ 1,14-5,34; р=0,03).
References
1. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 /J. McMurrey, S. Adamopoulus, S. Anker [et al.] // European Heart Journal. – 2012. –Vol. 33. – P. 1787-1847.
2. The current cost of heart failure to the national health service in UK / S. Stewart, A. Jenkins, S. Buchan [et al.] // Eur. Heart Fail. – 2002. – Vol. 4. – P.361-371.
3. Study protocol for the World Health Organisation project to develop a Quality of Life Assessment instrument // Quality of Life Research. – 1993. –Vol.2. – P. 153-158.
4. Балеева Е.С. Перспективы исследования качества жизни больных ишемической болезнью сердца / Е.С. Балеева, О.Ю. Алешкина // Бюл-летень медицинских интернет-коференций. – 2011. – №7. – С. 43-44.
5. Rabin R. EQ-5D: a measure of health status from the EuroQoL Group / R. Rabin, F. de Charro // Ann. Med. – 2001. – Vol. 5. – P. 337-343.
6. Rector T.S. Patients self - assessment of their congestive heart failure. Part 1: patient perceived dysfunction and its poor correlation with maximal exercise tests / T.S. Rector, G.S. Francis, G.N. Cohn // Heart failure. – 1987. – Vol.10, – P.192-196.
2. The current cost of heart failure to the national health service in UK / S. Stewart, A. Jenkins, S. Buchan [et al.] // Eur. Heart Fail. – 2002. – Vol. 4. – P.361-371.
3. Study protocol for the World Health Organisation project to develop a Quality of Life Assessment instrument // Quality of Life Research. – 1993. –Vol.2. – P. 153-158.
4. Балеева Е.С. Перспективы исследования качества жизни больных ишемической болезнью сердца / Е.С. Балеева, О.Ю. Алешкина // Бюл-летень медицинских интернет-коференций. – 2011. – №7. – С. 43-44.
5. Rabin R. EQ-5D: a measure of health status from the EuroQoL Group / R. Rabin, F. de Charro // Ann. Med. – 2001. – Vol. 5. – P. 337-343.
6. Rector T.S. Patients self - assessment of their congestive heart failure. Part 1: patient perceived dysfunction and its poor correlation with maximal exercise tests / T.S. Rector, G.S. Francis, G.N. Cohn // Heart failure. – 1987. – Vol.10, – P.192-196.
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Published
2019-07-08
How to Cite
Федоров, С. В., Глушко, Л. В., & Медвідь, А. Б. (2019). THE EFFECT OF IVABRADINE AND OMEGA-3 POLYUNSATURATED FATTY ACIDS FOR QUALITY OF LIFE OF PATIENTS WITH HEART FAILURE. PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Pulse, (4(28), 39–44. Retrieved from https://pvntsh.nung.edu.ua/index.php/pulse/article/view/803
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КЛІНІЧНА МЕДИЦИНА
