TY - JOUR AU - S. V. Fedorov, AU - I. V. Kozlova, AU - I.V. Martyniv, AU - O.S. Verbovska, AU - O.F. Sovtus, PY - 2022/12/28 Y2 - 2024/03/28 TI - STENT THROMBOSIS IN ACUTE PERIOD OF MYOCARDIAL INFACTION: CLINICAL PRESENTATION JF - PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Pulse JA - pulse VL - IS - 18 (66) SE - Статті DO - 10.21802/2304-7437-2022-18(66)-36-42 UR - https://pvntsh.nung.edu.ua/index.php/pulse/article/view/1861 SP - 36-42 AB - <p><em>Despite</em> <em>the</em> <em>progress</em> <em>of</em> <em>medical</em> <em>science,</em> <em>coronary</em> <em>artery</em> <em>disease</em> <em>remains</em> <em>the</em> <em>leader in the structure of morbidity and mortality. During the last decades, the main method of treatment of acute coronary syndrome is urgent percutaneous coronary intervention (PCI) with stent implantation in the infarct-related artery. One of the long-term complications after stenting is stent thrombosis, which negatively affects patient survival.</em></p><p><em>The</em> <em>purpose</em> <em>of</em> <em>the</em> <em>study:</em> <em>to</em> <em>describe</em> <em>a</em> <em>clinical</em> <em>case</em> <em>of</em> <em>early</em> <em>stent</em> <em>thrombosis</em> <em>in</em> <em>a</em> <em>patient</em> <em>with</em> <em>acute</em> <em>myocardial</em> <em>infarction</em> <em>and</em> <em>to</em> <em>analyze</em> <em>the possible causes of the mentioned complication after the procedure of PCI. А clinical case presentation of the development of early stent thrombosis after PCI in a patient with acute myocardial infarction (MI) is described and the main causes of this complication are analyzed. Female patient Sh., 65 years old, was urgently admitted with a preliminary diagnosis of acute coronary syndrome. On the 11th day after the PCI procedure, the patient’s general condition worsened - stent thrombosis was suspected and urgent coronary angiography was performed. According to the Academic Research Consortium classification, stent thrombosis is divided according to the level of confirmation and the time of development of the event. Clinical risk factors that contribute to the development of thrombosis are divided into three groups: depending on the procedure and type of atherosclerotic damage; dependent on the patient; dependent on antiplatelet therapy. Patients with ACS at high risk of thrombosis, who underwent PCI by means of stenting, require careful monitoring in the after-procedure period. The presence of diabetes, chronic kidney disease, heart failure, etc. is a prerequisite for prescribing more potent antiplatelet agents (ticagrelor, prasugrel) in addition to low doses of acetylsalicylic acid as part of dual antiplatelet therapy.</em></p><p><strong><em>Key words: </em></strong><em>acute coronary syndrome, myocardial infarction, diabetes, stent thrombosis</em></p> ER -