@article{Stetsevyat_Voronych-Semchenko_2019, title={THE INTENSITY OF OXIDATIVE MODIFICATION OF PROTEINS AND PEROXIDATION OF LIPIDS IN THE BLOOD SERUM, BRAIN, LIVER AND PANCREAS TISSUES OF RATS WITH INSULIN RESISTANCE AND CONGENITAL IODINE DEFICIENCY: Array}, url={https://pvntsh.nung.edu.ua/index.php/pulse/article/view/1230}, DOI={10.21802/2304-7437-2019-6(58)-115-120}, abstractNote={<p><em>The results of the study about the nature of oxygen-dependent processes in rats that were on a high-fructose diet for 8 weeks under conditions of adequate iodine supply and congenital iodine deprivation is </em><em>presented in the article</em><em>. The significant activation of peroxide oxidation of proteins (</em><em>by increasing the aldo- and keto-derivates of a neutral nature) and </em><em>lipids (increased of diene conjugates content and products, </em><em>that are responsible to thiobarbituric acid) of animals with insulin resistance was found.</em><em> An aggravating factor in the course of these processes is a congenital iodine deficiency. The changes of oxidative modification of proteins in animals with congenital iodine deficiency had multidirectional character, and processes of lipid peroxidation </em><em>mainly increased</em><em>. </em><em>The most pronounced changes of the studied processes were observed in the liver and pancreas of animals with insulin resistance against the background of congenital iodine deficiency.</em></p>}, number={6(58)}, journal={PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Pulse}, author={Stetsevyat, V. B. and Voronych-Semchenko, N. M.}, year={2019}, month={Dec.}, pages={115–120} }