• Н. Г. Вірстюк Ivano-Frankivsk National Medical University
  • О. Р. Лучко Ivano-Frankivsk National Medical University
  • Л. В. Лосюк Ivano-Frankivsk National Medical University
  • О. О. Хасанов Ivano-Frankivsk National Medical University
Keywords: unspecific ulcerous colitis, overintestinal defeat, index of endoscope activity, index of clinical activity.


Complex clinical and laboratory-instrumental research is conducted 30 patients with an unspecific ulcerous colitis (NVC). It is exposed, that the about half  of patients (53,3%) on NVC have overintestinal  displays, and in 43,8% cases overintestinal defeat the two and more of organs and systems. Among of overintestinal displays NVC the defeats of liver (56,3%) which varied from reactive hepatitis (44,4%) to the autoimmune defeats of liver, were most widespread, in particular autoimmune hepatitis (33,3%) and initial sclera holangite (22,3%).

It is set that at patients on NVC with autoimmune defeat of liver, spondiloartrite and psoriasis a clinical picture did not answer endoscope therefore by us the group of overintestinal defeats which insignificantly depend on activity of inflammatory process of mucus shell in a colon is selected. For other group characteristic was appearance of displays in the moment of high activity NVC and reduction or disappearance in the stage of remiss of disease – reactive arthritis, reactive hepatitis,  defeat of skin as key erythematic,  defeat of mucus shell of cavity of mouth and eyes.


1. Бойко Т. Й. Епідеміологія та чинники ризику хронічних неспецифічних запальних захворювань кишечнику / Т. Й. Бойко // Сучасна астроентерологія. – 2013. – № 4. – С. 129-134.
2. Дорофеев А.Э. Заболевания кишечника: Руководство для врачей / А.Э. Дорофеев, Т.Д. Звягинцева, Н.В. Харченко. – Горловка: ЧП «Ви-давництво «Ліхтар», 2010. – 552 с.
3. Електронний документ «Адаптована клінічна настанова, заснована на доказах «Неспецифічний виразковий коліт»», 2015.
4. Наказ МОЗ України від 11.02.2016 № 90 «Уніфікований клінічний протокол первинної, вторинної (спеціалізованої) та третинної (високо-спеціалізованої) медичної допомоги. Запальні захворювання кишечника (хвороба Крона, виразковий коліт)».
5. The Ulcerative Colitis Endoscopic Index of Severity More Accurately Reflects Clinical Outcomes and Long-term Prognosis than the Mayo Endoscopic Score / K. Ikeya, H. Hanai, K. Sugimoto [et al] // J. Cronns Colitis. – 2016. – Vol. 10(3). – P. 286-295. doi: 10.1093/ecco-jcc/jjv210.
6. Marín-Jiménez. Two-year incidence of new immune-mediated inflammatory diseases in patients with inflammatory bowel disease: A study in the AQUILES cohort / Marín-Jiménez, J.P. Gisbert, J.L. Pérez-Calle [et al.] // Gastroenterol Hepatol. – 2015. – Vol.38(10). – P. 569-74. doi: 10.1016/j.gastrohep.2015.04.003.
7. Ket S.N. Endoscopic Disease Activity in Inflammatory Bowel Disease / S.N. Ket, R. Palmer, S. Travis // Curr. Gastroenterol. Rep . – 2015. – Vol.17, No. 12. – P. 50. doi: 10.1007/s11894-015-0470-0.
8. Colonic biogeography in health and ulcerative colitis / А. Lavelle, G. Len-non, D.C. Winter [et al] // Gut. Microbes. – 2016. – Vol.7(5) . – P. 435-442.
9. The role of endoscopy in inflammatory bowel disease: GUIDELINE // A.K. Shergill, J.R. Lightdale, D.H. Bruining [et al] / 1121.e13 Gastrointest. Endoscopy. – 2015. – Vol. 81, No. 5. – P.1101-21. doi: 10.1016/j.gie. 2014.10.030.
10. Ouyang W. Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease / W. Ouyang // Cytokine Growth Factor Rev. – 2010. – Vol. 21(6). – P.435-41. doi: 10.1016/j.cytogfr.2010.10.007.
How to Cite
Вірстюк, Н. Г., Лучко, О. Р., Лосюк, Л. В., & Хасанов, О. О. (2019). CLINIC-LABORATORY AND ENDOSCOP FEATURES OF MOTION OF UNSPECIFIC ULCEROUS COLITIS. ПРИКАРПАТСЬКИЙ ВІСНИК НТШ Пульс, (4(36), 99-105. Retrieved from